Manchester United crashed out of the Europa League as a pitiful 3-0 defeat at the Ramon Sanchez Pizjuan Stadium saw Sevilla book their place in the semi-finals with a crushing 5-2 aggregate victory.
United threw away a two-goal first-leg advantage at Old Trafford with two own goals last week but stooped to new lows as Erik ten Hag's side imploded in Spain and saw their hopes of a treble of cups evaporate on a sobering night.
Harry Maguire's early error, which presented Youssef En-Nesyri with Sevilla's seventh-minute opener, set the tone for the insipid performance, which only got worse seconds after the break when Loic Bade's header looped in off the bar, and was then compounded by David De Gea's howler gifting En-Nesyri his second.
It was the latest in a series of demoralizing defeats which have come to characterize Ten Hag's debut season, and the worse possible preparation for Sunday's FA Cup semi-final against Brighton at Wembley, where United's remaining hopes of winning silverware now rest.
Sevilla's emphatic victory saw United bow out of Europe to Spanish opposition for the sixth successive time, while the six-time winners progress through to a semi-final against Juventus, who beat Sporting 2-1 in their quarter-final.